Salivary gland hypofunction is a frequent consequence of autoimmune disease and radiation therapy. Reproducible evaluation of salivary gland function in mouse models of these diseases is a technical challenge. Here, a simple method for accurate and reproducible measurement of saliva production in mice is described.
Bagavant, H., Trzeciak, M., Papinska, J., Biswas, I., Dunkleberger, M. L., Sosnowska, A., Deshmukh, U. S. A Method for the Measurement of Salivary Gland Function in Mice. J. Vis. Exp. (131), e57203, doi:10.3791/57203 (2018).