This paper explains the application of fluorescent imaging using an activatable optical imaging probe to visualize the in vivo activity of key matrix metalloproteinases in two different experimental models of inflammation.
Schwenck, J., Maier, F. C., Kneilling, M., Wiehr, S., Fuchs, K. Non-invasive In Vivo Fluorescence Optical Imaging of Inflammatory MMP Activity Using an Activatable Fluorescent Imaging Agent. J. Vis. Exp. (123), e55180, doi:10.3791/55180 (2017).