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A Robust Pneumonia Modell in intaktem Immunsystem Nagetiere zur Bewertung antibakterieller Wirksamkeit gegen<i> S. pneumoniae</i>,<i> H. influenzae</i>,<i> K. pneumoniae</i>,<em> P. aeruginosa</em> oder<em> A. baumannii</em
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A Robust Pneumonia Modell in intaktem Immunsystem Nagetiere zur Bewertung antibakterieller Wirksamkeit gegen<i> S. pneumoniae</i>,<i> H. influenzae</i>,<i> K. pneumoniae</i>,<em> P. aeruginosa</em> oder<em> A. baumannii</em
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January 02, 2017
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A method for establishing lung infections in immunocompetent rodents is described. With proficiency, this method can be performed quickly and easily to induce stable infection with many isolates of S. pneumoniae, H. influenzae, P. aeruginosa, K. pneumoniae and A. baumannii.
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Hoover, J. L., Lewandowski, T. F., Mininger, C. L., Singley, C. M., Sucoloski, S., Rittenhouse, S. A Robust Pneumonia Model in Immunocompetent Rodents to Evaluate Antibacterial Efficacy against S. pneumoniae, H. influenzae, K. pneumoniae, P. aeruginosa or A. baumannii. J. Vis. Exp. (119), e55068, doi:10.3791/55068 (2017).
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