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Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
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April 21, 2017
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Neonatal stroke is a significant cause of early brain injury requiring a translational model with consistent focal injury patterns and high reproducibility in order to enable study. This study describes the detailed surgical procedure for creating a non-hemorrhagic, unilateral focal ischemia-reperfusion injury in full-term-equivalent rodents.
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Larpthaveesarp, A., Gonzalez, F. F. Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats. J. Vis. Exp. (122), e54830, doi:10.3791/54830 (2017).
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