Rivista
/
Immunologia e infezioni
/
تقييم فعالية وسمية الرنا استهداف HIV-1 الإنتاج للاستخدام في الجينات أو العلاج بالعقاقير
JoVE Journal
Immunologia e infezioni
È necessario avere un abbonamento a JoVE per visualizzare questo.  Accedi o inizia la tua prova gratuita.
JoVE Journal Immunologia e infezioni
Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
Please note that all translations are automatically generated. Click here for the English version.

تقييم فعالية وسمية الرنا استهداف HIV-1 الإنتاج للاستخدام في الجينات أو العلاج بالعقاقير

7,713 Views

•

12:03 min

•

September 05, 2016

DOI:

10.3791/54486-v

DOI:
10.3791/54486-v

•

12:03 min
September 05, 2016

•

4 Views
, , , ,
1Virus-Cell Interactions Laboratory,Lady Davis Institute for Medical Research, 2Department of Microbiology & Immunology,McGill University, 3Department of Medicine,McGill University

Summary

Automatically generated

Methods to evaluate the efficacy and toxicity of RNA molecules targeting post-integration steps of the HIV-1 replication cycle are described. These methods are useful for screening new molecules and optimizing the format of existing ones.

Explore More Videos

RNAHIV-1Gene TherapyDrug TherapyEfficacyToxicityShort Hairpin RNASiRNARibozymeRNA Decoy293T CellsViral ProductionCell ViabilityImmune Activation

Read Article

Cite this Article

Scarborough, R. J., Adams, K. L., Del Corpo, O., Daher, A., Gatignol, A. Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy. J. Vis. Exp. (115), e54486, doi:10.3791/54486 (2016).

Download .ris file

Copy

Share Video

.

Copy