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Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration
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Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration
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May 19, 2016
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MRP4 regulates various cyclic nucleotide-dependent signaling events including a recently elucidated role in cell migration. We describe a direct, but multifaceted approach to unravel the downstream molecular targets of MRP4 resulting in identification of a unique MRP4 interactome that plays key roles in the fine-tuned regulation of fibroblast migration.
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Sinha, C., Arora, K., Naren, A. P. Methods to Study Mrp4-containing Macromolecular Complexes in the Regulation of Fibroblast Migration. J. Vis. Exp. (111), e53973, doi:10.3791/53973 (2016).
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