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The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration
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Medicina
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JoVE Journal Medicina
The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration

The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration

16,475 Views

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12:21 min

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November 26, 2015

DOI:

10.3791/53131-v

DOI:
10.3791/53131-v

•

12:21 min
November 26, 2015

•

2 Views
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1Department of Otolaryngology Head and Neck Surgery,Medical University of South Carolina, 2Department of Pathology and Laboratory Sciences,Medical University of South Carolina, 3Intuitive Surgical, Inc

Tags

Cochlear Cell DegenerationOtotoxic Agent DeliveryRound Window NicheCochlear InjuryAuditory PathophysiologyCochlear Cell RegenerationAnimal ModelHearing Loss

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Stevens, S. M., Brown, L. N., Ezell, P. C., Lang, H. The Mouse Round-window Approach for Ototoxic Agent Delivery: A Rapid and Reliable Technique for Inducing Cochlear Cell Degeneration. J. Vis. Exp. (105), e53131, doi:10.3791/53131 (2015).

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