Implanting organized arrays of microwires for use in single-unit electrophysiological recordings presents a number of technical challenges. Methods for performing this technique and the equipment necessary are described. Also, the beneficial use of organized microwire arrays to record from distinct neural subregions with high spatial selectivity is discussed.
Barker, D. J., Root, D. H., Coffey, K. R., Ma, S., West, M. O. A Procedure for Implanting Organized Arrays of Microwires for Single-unit Recordings in Awake, Behaving Animals. J. Vis. Exp. (84), e51004, doi:10.3791/51004 (2014).