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A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions
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Neuroscienze
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JoVE Journal Neuroscienze
A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

A Simple Stimulatory Device for Evoking Point-like Tactile Stimuli: A Searchlight for LFP to Spike Transitions

DOI:
10.3791/50941-v

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07:34 min

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March 25, 2014

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, , , , ,
1Institute of Molecular Bioimaging and Physiology (IBFM), Department of Biomedicine,National Research Council, 2Institute of Biomedical Technologies (ITB), Department of Biomedicine,National Research Council, 3Faculty of Life Sciences,University of Manchester

Capitoli

  • 00:05Titolo
  • 02:08Manufacture and Configuration of the Stimulation Device
  • 02:59Animal Preparation for Stereotaxic Surgery and Recording
  • 06:19Stimulation Protocol
  • 06:47Conclusion

Summary

Traduzione automatica

Traduzione automatica

To elucidate the complex transition from Local Field Potentials (LFPs) to spikes a suitable stimulator for light mechanical peripheral stimuli was built. As an application, the spiking activities recorded from somatosensory cortex were analyzed by a multi-objective optimization strategy. The results demonstrated that the proposed stimulator was able to deliver tactile stimuli with millisecond and millimeter precisions.

Tags

Tactile StimuliLocal Field Potentials (LFPs)Spike ActivityNeural CodingDeep Brain StimulationMulti-objective OptimizationSomatosensory CortexPiezoelectric ActuatorsPredictive Models

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