Rivista
/
Medicina
/
作为脑微血管内皮细胞（CEND）的伸展<em>体外</em创伤性脑损伤模型血脑屏障
JoVE Journal
Medicina
This content is Free Access.
JoVE Journal Medicina
Stretch in Brain Microvascular Endothelial Cells (cEND) as an In Vitro Traumatic Brain Injury Model of the Blood Brain Barrier
Please note that all translations are automatically generated. Click here for the English version.

作为脑微血管内皮细胞（CEND）的伸展<em>体外</em创伤性脑损伤模型血脑屏障

DOI:
10.3791/50928-v

•

07:19 min

•

October 26, 2013

•

, ,
1Klinik und Poliklinik für Anästhesiologie,Zentrum für operative Medizin der Universität Würzburg, 2Department of Medicinal Chemistry, Faculty of Life Sciences,University of Vienna

Capitoli

  • 00:05Titolo
  • 01:11Seeding of Endothelial Cells and Cell Differentiation
  • 02:50Stretch-induced Injury of Endothelial Cells
  • 03:46Assessment of Stretch Injury by Dye Uptake Assay and Lactate Dehydrogenase Release
  • 05:20Results: Stretch in Brain Microvascular Endothelial Cells as an In Vitro Traumatic Brain Injury Model of the Blood Brain Barrier
  • 06:50Conclusion

Summary

Traduzione automatica

Traduzione automatica

在体外创伤性脑损伤的车型正在研发中再现体内脑变形。伸展损伤已受聘为星形胶质细胞，神经元，神经胶质细胞，主动脉，脑血管内皮细胞。然而，我们的系统采用了血脑屏障（BBB）模型，该模型具有BBB构成一个合法的模型建立在体外 TBI模型的属性。

Tags

Traumatic Brain InjuryTBIIn Vitro ModelBrain Microvascular Endothelial CellsCENDBlood-brain BarrierBBBStretch InjuryPressure ApplicationCell PhysiologyIn Vivo TechniquesCell CultureExperimental Setup

Article

Embed

AGGIUNGI ALLA PLAYLIST

Usage Statistics

Video correlati

MRI引导下的破坏血脑屏障在大鼠模型经颅聚焦超声

允许有针对性的大鼠模型血 - 脑屏障破坏神经血管治疗

设置了一个<em>体外</em大鼠血脑屏障>模型（BBB）：在BBB抗渗性和受体介导的运输为中心

脑Microslices的兴奋性刺激作为<em>在体外</em>中风模型

控制皮层影响模型创伤性脑损伤

轻度脑外伤的幼年大鼠一种新模式

缺氧缺糖再给氧作为<em>在体外</em>缺血再灌注损伤模型的研究血脑屏障功能障碍

基于组织位移的小鼠脊髓损伤模型

单一和重复轻度创伤性脑损伤的小鼠模型

评估血脑屏障网状血管形成和破坏的体外测定

Read Article