È necessario avere un abbonamento a JoVE per visualizzare questo. Accedi o inizia la tua prova gratuita.
Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
18,083 Views
•
11:37 min
•
November 29, 2013
DOI:
Summary
Automatically generated
Protein conformation and dynamics are key to understanding the relationship between protein structure and function. Hydrogen exchange coupled with high-resolution mass spectrometry is a versatile method to study the conformational dynamics of proteins as well as characterizing protein-ligand and protein-protein interactions, including contact interfaces and allosteric effects.
Read Article
Cite this Article
Hentze, N., Mayer, M. P. Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry. J. Vis. Exp. (81), e50839, doi:10.3791/50839 (2013).
Copy