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应用生物标志物发现在前列腺癌：个别赫尔维位点表达微阵列鉴定
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November 02, 2013
DOI:
1Joint Unit Hospices de Lyon-bioMérieux, 2Medical Diagnostic Discovery Department,BioMérieux, 3Department of Pathology and Cytology, Centre Hospitalier Lyon Sud,Hospices Civils de Lyon, 4Medical Faculty,Lyon 1 University, 5Data and Knowledge Laboratory,BioMérieux, 6Department of Biochemistry and Molecular Biology, Centre Hospitalier Lyon Sud,Hospices Civils de Lyon, 7Department of Urology, Centre Hospitalier Lyon Sud,Hospices Civils de Lyon
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人内源性反转录病毒（HERV），它占据了人类基因组中的8％，保留稀缺编码能力，但一十万长末端重复序列（LTRs）。一个自定义的Affymetrix基因芯片的目的是找出个人赫尔维基因的表达，并用在前列腺癌组织的概念，为今后的临床研究证明。
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Pérot, P., Cheynet, V., Decaussin-Petrucci, M., Oriol, G., Mugnier, N., Rodriguez-Lafrasse, C., Ruffion, A., Mallet, F. Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer. J. Vis. Exp. (81), e50713, doi:10.3791/50713 (2013).
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