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寄生在鸡模型诱导自身免疫性基因驱动恰加斯心脏疾病
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July 29, 2012
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Parasite-inducedGenetically-drivenAutoimmuneChagas Heart DiseaseChicken ModelTrypanosoma CruziAcute InfectionsChronic InfectionsChagas DiseaseAutoimmunityParasite PersistenceT. Cruzi InoculationAir ChamberFertilized EggsMature Chicken Immune SystemParasite-free At HatchingParasite Mitochondrial Kinetoplast DNA (kDNA) Minicircle IntegrationTargeted Prime TAIL-PCRSouthern HybridizationsCloningSequencingRuptured Open Reading FramesTranscription FactorsImmune System FactorsPhosphatase (GTPase)Adenylate CyclasePhosphorylases (PKCNF-Kappa B ActivatorPI-3K)MyocarditisRejection Of Target Heart FibersCytotoxic Lymphocytes
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Teixeira, A. R. L., Nitz, N., Bernal, F. M., Hecht, M. M. Parasite Induced Genetically Driven Autoimmune Chagas Heart Disease in the Chicken Model. J. Vis. Exp. (65), e3716, doi:10.3791/3716 (2012).
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