A precise murine model for acute kidney injury (AKI) due to ischemia is an important tool to investigate acute kidney injury and possibly find therapeutic tools to treat renal injury. The hanging weight system offers a tool for immediate and reliable renal artery occlusion and reperfusion without causing renal congestion.
Grenz, A., Hong, J. H., Badulak, A., Ridyard, D., Luebbert, T., Kim, J., Eltzschig, H. K. Use of a Hanging-weight System for Isolated Renal Artery Occlusion. J. Vis. Exp. (53), e2549, doi:10.3791/2549 (2011).