This video shows experiments with subsequent analysis of protein-protein interactions by the use of micro-patterned surfaces. The approach offers the possibility to detect protein interactions in living cells and combines high throughput capabilities with the possibility to extract quantitative information.
Weghuber, J., Sunzenauer, S., Brameshuber, M., Plochberger, B., Hesch, C., Schutz, G. J. In-vivo Detection of Protein-protein Interactions on Micro-patterned Surfaces. J. Vis. Exp. (37), e1969, doi:10.3791/1969 (2010).