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PMS2 carente, ERCC1, Ku86, CcOI in Difetti del campo durante la progressione a tumore del colon
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28:15 min
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July 28, 2010
DOI:
1Department of Cell Biology and Anatomy, College of Medicine,University of Arizona, Tucson, 2Southern Arizona Veterans Affairs Health Care System,Tucson, AZ, 3Department of Surgery, College of Medicine,University of Arizona, Tucson, 4Biomedical Diagnostics and Research,Tucson, AZ, 5Department of Medicine, College of Medicine,University of Arizona, Tucson
Summary
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Ridotta espressione / assenza di PMS2 e / o ERCC1 nelle cripte intero è un evento frequente nel raggio di 10 cm su ogni lato degli adenocarcinomi del colon, probabilmente in base ad un difetto del campo con elevata mutevolezza e la progressione del cancro. Carenza di Ku86 o CcOI è molto meno frequente in questi difetti del campo.
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Cite this Article
Nguyen, H., Loustaunau, C., Facista, A., Ramsey, L., Hassounah, N., Taylor, H., Krouse, R., Payne, C. M., Tsikitis, V. L., Goldschmid, S., Banerjee, B., Perini, R. F., Bernstein, C. Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer. J. Vis. Exp. (41), e1931, doi:10.3791/1931 (2010).
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