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Low-stress Route Learning Using the Lashley III Maze in Mice
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09:14 min
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May 22, 2010
DOI:
1Department of Chemistry,Pennsylvania State University, 2Center for Developmental and Health Genetics,Pennsylvania State University, 3Department of Veterinary and Biomedical Sciences,Pennsylvania State University, 4Huck Institute of the Life Sciences,Pennsylvania State University, 5California NanoSystems Institute,University of California, Los Angeles, 6Semel Institute of Neuroscience and Human Behavior,University of California, Los Angeles
Summary
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The Lashley III maze is a route-learning task that does not rely on aversive stimuli or visual cues. It is thus a highly attractive option for evaluating learning and memory, especially in aging mice or otherwise where stress is a consideration.
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Bressler, A., Blizard, D., Andrews, A. Low-stress Route Learning Using the Lashley III Maze in Mice. J. Vis. Exp. (39), e1786, doi:10.3791/1786 (2010).
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