Chapter 24
Alternative Signaling Routes in Gene Expression
![Notch Signaling Pathway](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/11995.jpg)
The Notch signaling pathway is a major intracellular signaling pathway that is highly conserved over a broad spectrum of metazoan species. It stands…
![Canonical Wnt Signaling Pathway](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/11996.jpg)
The gene encoding the main signaling molecules of the Wnt signaling pathways (the Wnt proteins) was discovered almost four decades ago by…
![Hedgehog Signaling Pathway](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/11997.jpg)
The Hedgehog gene (Hh) was first discovered due to its control of the growth of disorganized, hair-like bristles phenotype in Drosophila, much like…
![NF-κB-dependent Signaling Pathway](https://jovecdn2.ccindex.cn/files/media/science-education/science-education-thumbs/11998.jpg)
The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the…
![Real-time Bioluminescence Imaging of Notch Signaling Dynamics during Murine Neurogenesis](https://jovecdn2.ccindex.cn/files/thumbs/60455_t.png)
Notch signaling regulates the maintenance of neural stem/progenitor cells by cell-cell interactions. The components of Notch signaling exhibit…
![Design and Analysis of Temperature Preference Behavior and its Circadian Rhythm in <em>Drosophila</em>](https://jovecdn2.ccindex.cn/files/thumbs/51097_t.png)
The circadian clock regulates many aspects of life, including sleep, locomotor activity, and body temperature (BTR) rhythms1,2. We recently…