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Accelerating Macromolecular Structural Analysis Using Smart Leginon Autoscreen

Accelerating Macromolecular Structural Analysis Using Smart Leginon Autoscreen

December 01, 2023

Author Spotlight: Enhancing Cryo-Electron Microscopy by Automated Data Collection and Analysis Techniques

01:41 min
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Using Smart Leginon Autoscreen for CryoEM Grid Screening

06:13 min
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1Simons Electron Microscopy Center, New York Structural Biology Center, 2Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology

Summary

Cryo-electron microscopy (cryoEM) multi-grid screening is often a tedious process that demands hours of attention. This protocol shows how to set up a standard Leginon collection and Smart Leginon Autoscreen to automate this process. This protocol can be applied to the majority of cryoEM holey foil grids.

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