David C. Irwin Department of Cardiology University of Colorado Denver Biography Publications Institution JoVE Articles David C. Irwin has not added a biography. If you are David C. Irwin and would like to personalize this page please email our Author Liaison for assistance. Publications Selective Depletion of Vascular EC-SOD Augments Chronic Hypoxic Pulmonary Hypertension American Journal of Physiology. Lung Cellular and Molecular Physiology. Oct, 2014 | Pubmed ID: 25326578 Aberrant Chloride Intracellular Channel 4 Expression Contributes to Endothelial Dysfunction in Pulmonary Arterial Hypertension Circulation. Apr, 2014 | Pubmed ID: 24503951 Nrf2 Activation: a Potential Strategy for the Prevention of Acute Mountain Sickness Free Radical Biology & Medicine. Oct, 2013 | Pubmed ID: 23722164 Hemoglobin-induced Endothelial Cell Permeability is Controlled, in Part, Via a Myeloid Differentiation Primary Response Gene-88-dependent Signaling Mechanism American Journal of Respiratory Cell and Molecular Biology. Oct, 2013 | Pubmed ID: 23713977 Upregulation of Phase II Enzymes Through Phytochemical Activation of Nrf2 Protects Cardiomyocytes Against Oxidant Stress Free Radical Biology & Medicine. Mar, 2013 | Pubmed ID: 23201694 Free Hemoglobin Induction of Pulmonary Vascular Disease: Evidence for an Inflammatory Mechanism American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2012 | Pubmed ID: 22728465 Selective Class I Histone Deacetylase Inhibition Suppresses Hypoxia-induced Cardiopulmonary Remodeling Through an Antiproliferative Mechanism Circulation Research. Mar, 2012 | Pubmed ID: 22282194 Cardiac HDAC6 Catalytic Activity is Induced in Response to Chronic Hypertension Journal of Molecular and Cellular Cardiology. Jul, 2011 | Pubmed ID: 21539845 Glutaraldehyde-polymerized Bovine Hemoglobin and Phosphodiesterase-5 Inhibition Critical Care Medicine. Jun, 2009 | Pubmed ID: 19384199 A Potential Role for Reactive Oxygen Species and the HIF-1alpha-VEGF Pathway in Hypoxia-induced Pulmonary Vascular Leak Free Radical Biology & Medicine. Jul, 2009 | Pubmed ID: 19358884 Polymerized Bovine Hemoglobin Decreases Oxygen Delivery During Normoxia and Acute Hypoxia in the Rat American Journal of Physiology. Heart and Circulatory Physiology. Sep, 2008 | Pubmed ID: 18567708 Pulmonary Edema Induced by Cerebral Hypoxic Insult in a Canine Model Aviation, Space, and Environmental Medicine. May, 2008 | Pubmed ID: 18500043 Neutral Endopeptidase Null Mice Are Less Susceptible to High Altitude-induced Pulmonary Vascular Leak High Altitude Medicine & Biology. 2005 | Pubmed ID: 16351565 Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats Gert Blueschke*1, Gabi Hanna*2, Andrew N. Fontanella2, Gregory M. Palmer2, Alina Boico2, Hooney Min2, Mark W. Dewhirst2, David C. Irwin3, Yulin Zhao2, Thies Schroeder4 1Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, 2Department of Radiation Oncology, Duke University Medical Center, 3Department of Cardiology, University of Colorado Denver, 4Department of Physical Chemistry, University of Mainz JoVE 51630 Medicina
Automated Measurement of Microcirculatory Blood Flow Velocity in Pulmonary Metastases of Rats Gert Blueschke*1, Gabi Hanna*2, Andrew N. Fontanella2, Gregory M. Palmer2, Alina Boico2, Hooney Min2, Mark W. Dewhirst2, David C. Irwin3, Yulin Zhao2, Thies Schroeder4 1Division of Plastic, Maxillofacial, and Oral Surgery, Duke University Medical Center, 2Department of Radiation Oncology, Duke University Medical Center, 3Department of Cardiology, University of Colorado Denver, 4Department of Physical Chemistry, University of Mainz JoVE 51630 Medicina