The present protocol describes the crystallization of microscopic ice crystals and clathrate hydrates in microfluidic devices, enabling liquid exchange around the formed crystals. This provides unparalleled possibilities to examine the crystallization process and binding mechanisms of the inhibitors.
Drori, R., Shalom, Y. A Microfluidic Approach for the Study of Ice and Clathrate Hydrate Crystallization. J. Vis. Exp. (186), e64072, doi:10.3791/64072 (2022).