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En human hornhindeorgankulturmodel for Descemets stripping kun med accelereret helbredelse stimuleret af konstrueret fibroblastvækstfaktor 1
Journal JoVE
Médecine
Author Produced
This content is Free Access.
Journal JoVE Médecine
A Human Corneal Organ Culture Model of Descemet’s Stripping Only with Accelerated Healing Stimulated by Engineered Fibroblast Growth Factor 1
DOI:

12:36 min

July 22, 2022

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Chapitres

  • 00:16Introduction
  • 02:27Wound Creation
  • 04:12Descemet’s Stripping
  • 05:51Trypan Blue Staining
  • 08:51Representative Results
  • 11:49Conclusion

Summary

Traduction automatique

Descemet's Stripping Only er en eksperimentel procedure, hvor patienter med central hornhinde guttae som følge af Fuchs Endothelial Corneal Dystrophy får Descemets membran strippet for perifere celler for at regenerere endotellaget. Vi præsenterer en ny metode, der simulerer DSO i dystrofiske humane hornhinden ex vivo med accelereret heling stimuleret af eFGF1 (NM141).

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