Expanding the Toolkit for <em>In Vivo</em> Imaging of Axonal Transport

Andrew P. Tosolini; David Villarroel-Campos; Giampietro Schiavo; James N. Sleigh

doi:10.3791/63471

Journal

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Neurosciences

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Ampliación del kit de herramientas para imágenes in vivo del transporte axonal

Journal JoVE
Neurosciences

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Journal JoVE Neurosciences

Expanding the Toolkit for In Vivo Imaging of Axonal Transport

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Ampliación del kit de herramientas para imágenes in vivo del transporte axonal

2,902 Views

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09:24 min

•

December 23, 2021

DOI:

10.3791/63471-v

DOI:

10.3791/63471-v

•

09:24 min

December 23, 2021

•

8 Views

Andrew P. Tosolini^1,2, David Villarroel-Campos^1,2,3, Giampietro Schiavo^1,2,3, James N. Sleigh^1,2,3

¹Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology,University College London, ²UCL Queen Square Motor Neuron Disease Centre,University College London, ³UK Dementia Research Institute,University College London

Summary

Utilizando ratones fluorescentes transgénicos, se describen protocolos detallados para evaluar el transporte axonal in vivo de endosomas de señalización y mitocondrias dentro de los axones motores y sensoriales del nervio ciático intacto en animales vivos.

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Ampliación del kit de herramientas para imágenes in vivo del transporte axonal

Summary

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