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Espansione del toolkit per l'imaging in vivo del trasporto assonale
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Expanding the Toolkit for In Vivo Imaging of Axonal Transport
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Espansione del toolkit per l'imaging in vivo del trasporto assonale

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09:24 min

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December 23, 2021

DOI:

10.3791/63471-v

DOI:
10.3791/63471-v

•

09:24 min
December 23, 2021

•

8 Views
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1Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology,University College London, 2UCL Queen Square Motor Neuron Disease Centre,University College London, 3UK Dementia Research Institute,University College London

Summary

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Utilizzando topi fluorescenti transgenici, vengono descritti protocolli dettagliati per valutare il trasporto assonale in vivo di endosomi e mitocondri di segnalazione all'interno di assoni motori e sensoriali del nervo sciatico intatto in animali vivi.

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Tosolini, A. P., Villarroel-Campos, D., Schiavo, G., Sleigh, J. N. Expanding the Toolkit for In Vivo Imaging of Axonal Transport. J. Vis. Exp. (178), e63471, doi:10.3791/63471 (2021).

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