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Mechanical Conflict-Avoidance Assay to Measure Pain Behavior in Mice
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Journal JoVE Neurosciences
Mechanical Conflict-Avoidance Assay to Measure Pain Behavior in Mice

Mechanical Conflict-Avoidance Assay to Measure Pain Behavior in Mice

3,290 Views

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06:57 min

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February 18, 2022

DOI:

10.3791/63454-v

DOI:
10.3791/63454-v

•

06:57 min
February 18, 2022

•

15 Views
, , , ,
1Laboratories of Neuroimmunology, Department of Symptom Research, and the MD Anderson Pain Research Consortium,University of Texas MD Anderson Cancer Center, 2Department of Anesthesiology, Perioperative and Pain Medicine,Stanford University School of Medicine

Summary

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The mechanical conflict-avoidance assay is used as a non-reflexive readout of pain sensitivity in mice which can be used to better understand affective-motivational responses in a variety of mouse pain models.

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Cite this Article

Gaffney, C. M., Muwanga, G., Shen, H., Tawfik, V. L., Shepherd, A. J. Mechanical Conflict-Avoidance Assay to Measure Pain Behavior in Mice. J. Vis. Exp. (180), e63454, doi:10.3791/63454 (2022).

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