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Imaging and Quantification of Intact Neuronal Dendrites via CLARITY Tissue Clearing
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Imaging and Quantification of Intact Neuronal Dendrites via CLARITY Tissue Clearing
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07:45 min
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April 20, 2021
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Neuronal dendritic morphology often underlies function. Indeed, many disease processes that affect the development of neurons manifest with a morphological phenotype. This protocol describes a simple and powerful method for analyzing intact dendritic arbors and their associated spines.
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Pekarek, B. T., Hunt, P. J., Belfort, B. D. W., Liu, G., Arenkiel, B. R. Imaging and Quantification of Intact Neuronal Dendrites via CLARITY Tissue Clearing. J. Vis. Exp. (170), e62532, doi:10.3791/62532 (2021).
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