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A Modified Surgical Model of Hind Limb Ischemia in ApoE-/- Mice using a Miniature Incision
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Journal JoVE Biologie
A Modified Surgical Model of Hind Limb Ischemia in ApoE-/- Mice using a Miniature Incision

A Modified Surgical Model of Hind Limb Ischemia in ApoE-/- Mice using a Miniature Incision

DOI:
10.3791/62402-v

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05:47 min

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May 13, 2021

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, , , , ,
1Department of Surgery, Medical Faculty Manheim,Heidelberg University, 2European Center of Angioscience ECAS, Medical Faculty Manheim,Heidelberg University, 3Computer-Assisted Clinical Medicine, Mannheim Institute for Intelligent Systems in Medicine, Medical Faculty Mannheim,Heidelberg University, 4Cooperative Core Facility Animal Scanner ZI, Medical Faculty Mannheim,Heidelberg University

Chapitres

  • 00:04Introduction
  • 00:54Induction of HLI in ApoE& #8211;/– Mice
  • 03:22Results: DLFA Surgery Using Miniature Incision to Establish HLI Model
  • 05:05Conclusion

Summary

Traduction automatique

Traduction automatique

This article demonstrates an efficient surgical approach to establish acute ischemia in mice with a small incision. This approach can be applied by most research groups without any laboratory upgrades.

Tags

Keywords: Hind Limb IschemiaApoE-/- MiceModified Surgical ModelMiniature IncisionLow InvasivenessInguinal RegionFemoral ArteryFemoral NerveFemoral VeinAbsorbable SuturesNeurovascular BundleMicrosurgical Model

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