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Journal
/
Immunologie et infection
/
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Journal JoVE
Immunologie et infection
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Journal JoVE
Immunologie et infection
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
DOI:
10.3791/62195-v
•
08:31 min
•
September 20, 2021
•
Tejabhiram Yadavalli
,
Ipsita Volety
,
Deepak Shukla
2
1
Department of Ophthalmology and Visual Sciences
,
University of Illinois at Chicago
,
2
Department of Microbiology and Immunology
,
University of Illinois at Chicago
Chapitres
00:05
Introduction
01:14
Whole Eye Porcine Cornea Isolation
02:55
Visualization
03:32
Vero
Cell Preparation
04:19
Virus Collection
05:21
Virus Infection Quantification
06:52
Results: Representative Viral Spread Infection Evaluation
07:38
Conclusion
Summary
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We describe the use of a porcine cornea to test the antiviral efficacy of experimental drugs.
Tags
Herpes Simplex Virus-1 Antivirals
Animal Models
In Vitro Testing
Cornea Isolation
Cornea Maintenance
Virus Infection
17 GFP Virus
Article
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