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Assessment of Memory Function in Pilocarpine-induced Epileptic Mice
Journal JoVE
Sciences du comportement
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Journal JoVE Sciences du comportement
Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

Assessment of Memory Function in Pilocarpine-induced Epileptic Mice

DOI:

13:34 min

June 04, 2020

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Chapitres

  • 00:04Introduction
  • 00:44Novel Object Location Test (NL)
  • 05:34Novel Object Recognition Test (NO)
  • 08:18Pattern Separation Test (PS)
  • 11:13Results: Behavioral Apparatus, Spatial Memory, and Neuronal Death
  • 12:32Conclusion

Summary

Traduction automatique

This article presents experimental procedures for assessing memory impairments in pilocarpine-induced epileptic mice. This protocol can be used to study the pathophysiologic mechanisms of epilepsy-associated cognitive decline, which is one of the most common comorbidities in epilepsy.

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