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Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures

Purkinje Cell Survival in Organotypic Cerebellar Slice Cultures

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06:31 min

December 18, 2019

DOI:

06:31 min
December 18, 2019

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Summary

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Organotypic slice cultures are a powerful tool to study neurodevelopmental or degenerative/regenerative processes. Here, we describe a protocol that models the neurodevelopmental death of Purkinje cells in mouse cerebellar slice cultures. This method may benefit research in neuroprotective drug discovery.

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