Journal
/
Sciences du comportement
/
Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice
Journal JoVE
Sciences du comportement
This content is Free Access.
Journal JoVE Sciences du comportement
Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice

15,047 Views

•

09:34 min

•

June 19, 2019

DOI:

10.3791/59598-v

DOI:
10.3791/59598-v

•

09:34 min
June 19, 2019

•

12 Views
, , , , , ,
1Dept. of Stress Neurobiology and Neurogenetics,Max Planck Institute of Psychiatry, 2Graduate School of Systemic Neurosciences,Ludwig Maximilians University, 3Max Planck Florida Institute for Neuroscience, 4Dept. of Neurobiology,Weizmann Institute of Science

Summary

Automatically generated

This method describes a chronic preparation that allows optical access to the hippocampus of living mice. This preparation can be used to perform longitudinal optical imaging of neuronal structural plasticity and activity-evoked cellular plasticity over a period of several weeks.

Explore More Videos

Two-photon ImagingDorsal HippocampusCA1Live MiceLongitudinalMemory FormationMemory RecallAlzheimer’s DiseaseSurvival SurgeryImaging CannulaUV CuringDental DrillLambdaBregmaLidocainePeriosteum

Read Article

Cite this Article

Ulivi, A. F., Castello-Waldow, T. P., Weston, G., Yan, L., Yasuda, R., Chen, A., Attardo, A. Longitudinal Two-Photon Imaging of Dorsal Hippocampal CA1 in Live Mice. J. Vis. Exp. (148), e59598, doi:10.3791/59598 (2019).

Download .ris file

Copy

Share Video

.

Copy