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1Department of Biomedical Engineering, School of Medicine, School of Engineering,University of Alabama at Birmingham, 2Division of Cardiovascular Diseases, School of Medicine, School of Engineering,University of Alabama at Birmingham, 3Department of Cardiac Surgery,The Second Xiangya Hospital of Central South University
Chapitres
- 00:04Titre
- 01:13hiPSC-CMs Purification, Small Molecule Pre-treatment, Myocardial Infarction, and Cell Transplantation
- 03:42Calcium Transient and Contractility Recording
- 05:21Results: Increased Engraftment of Transplanted hiPSC-CM Preconditioned with the ROCK Inhibitor Y-27632 in a Murine MI Model
- 07:11Conclusion
I denne protokollen, viser vi og utdype hvordan du bruker humant indusert Pluripotent stamceller for cardiomyocyte differensiering og rensing, og videre, om hvordan å forbedre sin transplantasjon effektivitet med Rho-assosiert protein kinase inhibitor forbehandling i en mus hjerteinfarkt modell.
