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Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain
Journal JoVE
Médecine
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Journal JoVE Médecine
Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

Spontaneous and Evoked Measures of Pain in Murine Models of Monoarticular Knee Pain

DOI:
10.3791/59024-v

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08:03 min

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February 22, 2019

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, , , ,
1Department of Medicine,University of Minnesota, 2Research Department,VA Health Care Center

Chapitres

  • 00:04Titre
  • 00:50Intra-Articular Knee Injections
  • 01:31Evoked Joint Pain Measurement
  • 02:49Spontaneous Joint Pain Measurement
  • 06:06Results: Representative Evoked and Spontaneous Pain Measures in Murine Models of Monoarticular Knee Pain
  • 07:39Conclusion

Summary

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Traduction automatique

We have developed an evoked measure of arthritis pain and coupled it with a standardized method for measuring spontaneous pain in different murine models of chemically induced arthritis. These measures are sensitive and reproducible for different types of joint pain.

Tags

Keywords: Pain MeasurementArthritisPre-clinical ModelsEvoked PainSpontaneous PainKnee PainAnesthetized MouseJoint InjectionAlgometryVocalizationDynamic Weight Bearing

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