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豊かにし、磁性ナノ粒子でまれな抗原特異的 T 細胞を展開
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Journal JoVE Ingénierie
Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles
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豊かにし、磁性ナノ粒子でまれな抗原特異的 T 細胞を展開

11,268 Views

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09:28 min

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November 17, 2018

DOI:

10.3791/58640-v

DOI:
10.3791/58640-v

•

09:28 min
November 17, 2018

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6 Views
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1Department of Biomedical Engineering, School of Medicine,Johns Hopkins University, 2Institute for Cell Engineering, School of Medicine,Johns Hopkins University, 3Institute for Nanobiotechnology,Johns Hopkins University, 4Department of Pathology, School of Medicine,Johns Hopkins University

Summary

Automatically generated

抗原特異的 T 細胞は特性またはその極低周波による治療を利用しにくい。本明細書で我々 はこれらの細胞を豊かにする抗原特異的 T 細胞に結合することができます磁性粒子を開発するためのプロトコルを提供し、それらをいくつか展開する特性評価および治療の両方の 100 倍。

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Cite this Article

Hickey, J. W., Schneck, J. P. Enrich and Expand Rare Antigen-specific T Cells with Magnetic Nanoparticles. J. Vis. Exp. (141), e58640, doi:10.3791/58640 (2018).

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