This protocol describes the process of applying seven different automated segmentation tools to structural T1-weighted MRI scans to delineate grey matter regions that can be used for the quantification of grey matter volume.
Johnson, E. B., Scahill, R. I., Tabrizi, S. J. Automated Segmentation of Cortical Grey Matter from T1-Weighted MRI Images. J. Vis. Exp. (143), e58198, doi:10.3791/58198 (2019).