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Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

Journal JoVE
Neurosciences

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Journal JoVE Neurosciences

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

Modelling Zika Virus Infection of the Developing Human Brain In Vitro Using Stem Cell Derived Cerebral Organoids

10,154 Views

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09:18 min

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September 19, 2017

DOI:

10.3791/56404-v

DOI:

10.3791/56404-v

•

09:18 min

September 19, 2017

•

4 Views

Max R Salick*¹, Michael F Wells*^2,3, Kevin Eggan³, Ajamete Kaykas

¹Department of Neuroscience,Novartis Institutes for BioMedical Research, ²Stanley Center for Psychiatric Research,Broad Institute of MIT and Harvard, ³Department of Stem Cell and Regenerative Biology and Harvard Stem Cell Institute,Harvard University

Tags

Zika Virus Cerebral Organoids Stem Cell In Vitro Model Cell Culture Cell Dissociation ROCK Inhibitor High-throughput Assay CRISPR Drug Screening Virus Pseudotyping

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