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用四甲基铵进行实时离子电渗疗法，以量化体细胞分数和脑细胞外空间的变性
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10:45 min
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July 24, 2017
DOI:
1Department of Medicine,University of Virginia, 2Department of Cell Biology,SUNY Downstate Medical Center, 3Neural and Behavioral Science Graduate Program,SUNY Downstate Medical Center, 4Division of Neonatology,University of Virginia, 5Department of Neuroscience and Physiology,New York University School of Medicine
Summary
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该方案描述了实时离子电渗疗法，一种测量活体大脑细胞外空间（ECS）物理参数的方法。释放到ECS中的惰性分子的扩散用于计算ECS体积分数和曲折度。它是研究脑ECS急性可逆变化的理想选择。
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Cite this Article
Odackal, J., Colbourn, R., Odackal, N. J., Tao, L., Nicholson, C., Hrabetova, S. Real-time Iontophoresis with Tetramethylammonium to Quantify Volume Fraction and Tortuosity of Brain Extracellular Space. J. Vis. Exp. (125), e55755, doi:10.3791/55755 (2017).
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