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The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury
Journal JoVE
Médecine
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Journal JoVE Médecine
The Rabbit Model of Accelerated Atherosclerosis: A Methodological Perspective of the Iliac Artery Balloon Injury
DOI:

09:14 min

October 03, 2017

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Chapitres

  • 00:05Titre
  • 01:13Surgical Preparations
  • 03:02Iliac Artery Ballon Injury Surgery
  • 05:21Post-operative Care
  • 06:00Tissue Harvesting and Analysis of Plaque Composition
  • 07:05Résultats
  • 08:41Conclusion

Summary

Traduction automatique

Animal models of atherosclerosis are essential to understand the mechanism and to investigate newer approaches to prevent plaque development or rupture, a leading cause of death in the industrialized world. This protocol uses a combination of balloon injury and cholesterol rich diet to induce atherosclerotic plaques in rabbit iliac artery.

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