Set-shifting, a form of behavioral flexibility, requires an attentional shift from one stimulus dimension to another. We extended an established rodent set-shifting task1 by requiring attention to different stimuli according to context. The task was combined with specific lesions to identify neuron subtypes underlying a successful shift.
Aoki, S., Liu, A. W., Zucca, A., Zucca, S., Wickens, J. R. New Variations for Strategy Set-shifting in the Rat. J. Vis. Exp. (119), e55005, doi:10.3791/55005 (2017).