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Chapitres
- 00:05Titre
- 00:58Fixing and Paraffin-embedding Drosophilia Heads
- 02:36Sectioning, Mounting, and Microscopy
- 04:38Results: Mass Histology Allows for Large-scale Analysis of Neurodegeneation in Drosophila
- 05:59Conclusion
Drosophila is widely used as a model system to study neurodegeneration. This protocol describes a method by which degeneration, as determined by vacuole formation in the brain, can be quantified. It also minimizes effects due to the experimental procedure by processing and sectioning control and experimental flies as one sample.
