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Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice
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September 28, 2015
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Subcutaneous implantation of osmotic pumps provides a convenient approach for prolonged and consistent delivery of compounds. This approach has been used extensively to study both abdominal and thoracic aortic aneurysms in mice.
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Lu, H., Howatt, D. A., Balakrishnan, A., Moorleghen, J. J., Rateri, D. L., Cassis, L. A., Daugherty, A. Subcutaneous Angiotensin II Infusion using Osmotic Pumps Induces Aortic Aneurysms in Mice. J. Vis. Exp. (103), e53191, doi:10.3791/53191 (2015).
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