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Médecine
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Используя мышиный INDUCIBLE теломеразы аллелей в исследованиях ткани дегенерации / регенерации и Рака
Journal JoVE
Médecine
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Journal JoVE Médecine
Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer
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Используя мышиный INDUCIBLE теломеразы аллелей в исследованиях ткани дегенерации / регенерации и Рака

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08:34 min

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April 13, 2015

DOI:

10.3791/52599-v

DOI:
10.3791/52599-v

•

08:34 min
April 13, 2015

•

3 Views
, , , , , ,
1Department of Cancer Biology,UT MD Anderson Cancer Center, 2Novartis Institutes for Biomedical Research, 3Sanofi US, 4Institute of Applied Cancer Science,UT MD Anderson Cancer Center

Summary

Automatically generated

Telomere and telomerase play essential roles in ageing and tumorigenesis. The goal of this protocol is to show how to generate two murine inducible telomerase knock-in alleles and how to utilize them in the studies of tissue degeneration/regeneration and cancer.

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Cite this Article

Shingu, T., Jaskelioff, M., Yuan, L., Ding, Z., Protopopov, A., Kost-Alimova, M., Hu, J. Utilizing Murine Inducible Telomerase Alleles in the Studies of Tissue Degeneration/Regeneration and Cancer. J. Vis. Exp. (98), e52599, doi:10.3791/52599 (2015).

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