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Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration
Journal JoVE
Médecine
Author Produced
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Journal JoVE Médecine
Renal Ischaemia Reperfusion Injury: A Mouse Model of Injury and Regeneration
DOI:

12:27 min

June 07, 2014

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Chapitres

  • 00:00Titre
  • 01:36Surgical Preparation
  • 02:49Laparotomy and Ureter Division
  • 03:59Right Nephrectomy
  • 05:10Left Kidney Ischaemia and Reperfusion
  • 08:06Representative Results: Injury
  • 09:34Representative Results: Regeneration
  • 11:30Conclusion

Summary

Traduction automatique

The mouse model of renal ischaemia reperfusion injury described here comprises of a right nephrectomy that provides control tissue and clamping of the left renal pedicle to induce ischaemia that results in acute kidney injury. This model uses a midline laparotomy approach with all steps performed via one incision.

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