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In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves
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Journal JoVE Neurosciences
In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves

32,170 Views

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11:07 min

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April 13, 2014

DOI:

10.3791/51181-v

DOI:
10.3791/51181-v

•

11:07 min
April 13, 2014

•

58 Views
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1Leibniz Institute for Age Research,Fritz Lipmann Institute, 2Friedrich Schiller University Jena, 3Institute of Molecular Cell Biology & Center for Sepsis Control and Care (CSCC) Jena University Hospital,Friedrich Schiller University Jena

Summary

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Measurements of nerve conduction properties in vivo exemplify a powerful tool to characterize various animal models of neuromuscular diseases. Here, we present an easy and reliable protocol by which electrophysiological analysis on sciatic nerves of anesthetized mice can be performed.

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Cite this Article

Schulz, A., Walther, C., Morrison, H., Bauer, R. In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves. J. Vis. Exp. (86), e51181, doi:10.3791/51181 (2014).

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