Journal
/
Chimie
/
Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Journal JoVE
Chimie
Author Produced
Un abonnement à JoVE est nécessaire pour voir ce contenu.  Connectez-vous ou commencez votre essai gratuit.
Journal JoVE Chimie
Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes

DOI:
10.3791/50886-v

•

12:27 min

•

September 08, 2013

•

, ,
1Department of Chemistry and Biochemistry,University of North Carolina at Greensboro

Chapitres

  • 00:00Titre
  • 03:46Synthesis of Phenyl HIAT
  • 05:35Synthesis of n-Pentyl HIAT
  • 08:33O-H insertion cyanocarbene reaction using Phenyl HIAT
  • 10:17Cylcopropanation cyanocarbene reaction using Phenyl HIAT
  • 11:50Conclusion

Summary

Traduction automatique

Traduction automatique

Herein is described the synthesis, isolation, and reactions of hypervalent iodonium alkynyl triflates (HIATs) with azides to generate cyanocarbenes. The procedures will involve air-sensitive and cryogen techniques, including cold filtration under an inert atmosphere. Handling and safety of the synthesized compounds will also be discussed.

Tags

Hypervalent Iodonium Alkynyl TriflatesCyanocarbenesAzidesO-H InsertionSulfoxide ComplexationCyclopropanationVinylidene-carbeneHypervalent Iodonium Alkenyl Triflate

Article

Embed

AJOUTER À LA PLAYLIST

Usage Statistics

Vidéos Connexes

Synthesis, Cellular Delivery and In vivo Application of Dendrimer-based pH Sensors

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives

HKUST-1 as a Heterogeneous Catalyst for the Synthesis of Vanillin

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

Facile Synthesis of Worm-like Micelles by Visible Light Mediated Dispersion Polymerization Using Photoredox Catalyst

Synthesis and Mass Spectrometry Analysis of Oligo-peptoids

Synthesis of Substrate-Bound Au Nanowires Via an Active Surface Growth Mechanism

Synthesis of Soft Polysiloxane-urea Elastomers for Intraocular Lens Application

Synthesis and Bioconjugation of Thiol-Reactive Reagents for the Creation of Site-Selectively Modified Immunoconjugates

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides

Read Article