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Intraductal Injection for Lokalisert Drug Deli til musemelkekjertlene
Journal JoVE
Biologie
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Journal JoVE Biologie
Intraductal Injection for Localized Drug Delivery to the Mouse Mammary Gland

Intraductal Injection for Lokalisert Drug Deli til musemelkekjertlene

DOI:
10.3791/50692-v

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06:39 min

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October 04, 2013

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, ,
1Vascular Biology Program, Department of Surgery,Boston Children’s Hospital and Harvard Medical School, 2Wyss Institute for Biologically Inspired Engineering,Harvard University, 3Harvard School of Engineering and Applied Sciences

Chapitres

  • 00:05Titre
  • 01:16Pre-operative Preparation
  • 02:48Intraductal Injection and Analysis of Mammary Gland Tissue
  • 05:02Results: Mammary Gland Injections Enable Localized Delivery of Molecules
  • 06:15Conclusion

Summary

Traduction automatique

Traduction automatique

En protokoll for den ikke-invasive intraductal levering av vandige reagenser til musemelkekjertlene er beskrevet. Metoden utnytter lokalisert injeksjon i brystvortene av melkekjertlene rettet mot melkegangene spesielt. Denne teknikken kan tilpasses for en rekke forbindelser inkludert siRNA, kjemoterapeutiske midler og små molekyler.

Tags

Keywords: Intraductal InjectionLocalized Drug DeliveryMouse Mammary GlandEvans BlueFluorescent ReagentsNon-invasiveSiRNAChemotherapeutic AgentsSmall Molecules

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