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Generation und 3-Dimensional Quantifizierung der arterielle Läsionen in Mäuse mit optischen Projektionstomographie
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May 26, 2015
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Ex vivo analysis of arterial lesions from animal models of cardiovascular disease classically relies on histological and immunohistochemical techniques. These provide 2-dimensional measurements in 3-dimensional lesions. This manuscript describes the generation of arterial lesions for quantitative analysis in 3-dimensions using optical projection tomography.
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Kirkby, N. S., Low, L., Wu, J., Miller, E., Seckl, J. R., Walker, B. R., Webb, D. J., Hadoke, P. W. F. Generation and 3-Dimensional Quantitation of Arterial Lesions in Mice Using Optical Projection Tomography. J. Vis. Exp. (99), e50627, doi:10.3791/50627 (2015).
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