Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Jeffrey S. Phillips; Adam S. Greenberg; John A. Pyles; Sudhir K. Pathak; Marlene Behrmann; Walter Schneider; Michael J. Tarr

doi:10.3791/4125

Journal

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Neurosciences

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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Neurosciences

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Journal JoVE Neurosciences

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

25,741 Views

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17:06 min

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November 08, 2012

DOI:

10.3791/4125-v

DOI:

10.3791/4125-v

•

17:06 min

November 08, 2012

•

12 Views

Jeffrey S. Phillips^1,2, Adam S. Greenberg^1,3, John A. Pyles^1,3, Sudhir K. Pathak^1,4, Marlene Behrmann^1,3, Walter Schneider^1,3, Michael J. Tarr^1,3

¹Center for the Neural Basis of Cognition, ²Department of Psychology,University of Pittsburgh, ³Department of Psychology,Carnegie Mellon University , ⁴Department of Bioengineering,University of Pittsburgh

Summary

We describe a novel approach for simultaneous analysis of brain function and structure using magnetic resonance imaging (MRI). We assess brain structure with high-resolution diffusion-weighted imaging and white-matter fiber tractography. Unlike standard structural MRI, these techniques allow us to directly relate anatomical connectivity to functional properties of brain networks.

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Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

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