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Habituation and Prepulse Inhibition of Acoustic Startle in Rodents
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September 01, 2011
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Habituation and prepulse inhibition of startle are operational measures of sensory gating. Sensory gating is disrupted in schizophrenia, and some other mental disorders and neurodegenerative diseases. We here describe a standard protocol to assess short-term and long-term habituation as well as prepulse inhibition of acoustic startle responses in rats and mice.
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Valsamis, B., Schmid, S. Habituation and Prepulse Inhibition of Acoustic Startle in Rodents. J. Vis. Exp. (55), e3446, doi:10.3791/3446 (2011).
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