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Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures
Journal JoVE
Neurosciences
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Journal JoVE Neurosciences
Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

Multi-electrode Array Recordings of Neuronal Avalanches in Organotypic Cultures

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16:01 min

August 01, 2011

DOI:

16:01 min
August 01, 2011

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Summary

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A robust way to study neuronal avalanches, i.e. scale-invariant spatio-temporal activity bursts, indicative of critical state dynamics in cortex. Avalanches emerge spontaneously in developing superficial layers of cultured cortex which allows for long-term measurements of the activity with planar integrated multi-electrode arrays (MEA) under precisely controlled conditions.

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